Facilitation in sea anemones; the action of drugs.

نویسنده

  • D M ROSS
چکیده

In a series of papers on the nerve net of the Actinozoa, Pantin (19350, b, c, d) showed that the decisive factor in the neuromuscular activity of these animals is an extreme development of facilitation. This is seen most readily in the transmission of excitation from the nerve net to certain muscleo, in particular the marginal sphincter of Calliactis parasitica and the longitudinal mesenteric muscles of Metridium senile. These muscles do not respond to a single electrical stimulus applied to the nerve net, but a second stimulus following soon after causes an immediate contraction. This means that a single stimulus which has no visible effect leaves behind it an effect which facilitates the transmission of a second impulse to the muscle. This facilitating effect of a stimulus dies away gradually, and it is the interval between stimuli, or the amount of facilitation, which determines the size of the response. This contrasts sharply with the mechanism in vertebrate skeletal muscle, where the strength of the stimulus determines the size of the response.

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عنوان ژورنال:
  • The Journal of experimental biology

دوره 22  شماره 

صفحات  -

تاریخ انتشار 1945